Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61640
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
2595.255±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61640
Synonyms:
(4-fluorobenzyl)-(6-methoxy-2-methyl-4-quinolyl)amine | MLS001173050 | N-[(4-fluorophenyl)methyl]-6-methoxy-2-methyl-4-quinolinamine | N-[(4-fluorophenyl)methyl]-6-methoxy-2-methyl-quinolin-4-amine | N-[(4-fluorophenyl)methyl]-6-methoxy-2-methylquinolin-4-amine | SMR000590021 | cid_4798059
Type:
Small organic molecule
Emp. Form.:
C18H17FN2O
Mol. Mass.:
296.3388
SMILES:
COc1ccc2nc(C)cc(NCc3ccc(F)cc3)c2c1
Structure:
Search PDB for entries with ligand similarity: