Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61781
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61781
Synonyms:
(4-benzhydrylpiperazin-1-yl)-[5-(3-hydroxyphenyl)-1,2-oxazol-3-yl]methanone | (4-benzhydrylpiperazino)-[5-(3-hydroxyphenyl)isoxazol-3-yl]methanone | MLS000116285 | SMR000093262 | [4-(diphenylmethyl)-1-piperazinyl]-[5-(3-hydroxyphenyl)-3-isoxazolyl]methanone | [4-(diphenylmethyl)piperazin-1-yl]-[5-(3-hydroxyphenyl)-1,2-oxazol-3-yl]methanone | cid_5309420
Type:
Small organic molecule
Emp. Form.:
C27H25N3O3
Mol. Mass.:
439.5057
SMILES:
Oc1cccc(c1)-c1cc(no1)C(=O)N1CCN(CC1)C(c1ccccc1)c1ccccc1
Structure:
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