Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61790
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61790
Synonyms:
1-(2-isopropyl-5-methyl-cyclohexoxy)-3-(1-phenylethylamino)propan-2-ol;hydrochloride | 1-(5-methyl-2-propan-2-yl-cyclohexyl)oxy-3-(1-phenylethylamino)propan-2-ol;hydrochloride | 1-(5-methyl-2-propan-2-ylcyclohexyl)oxy-3-(1-phenylethylamino)-2-propanol;hydrochloride | 1-(5-methyl-2-propan-2-ylcyclohexyl)oxy-3-(1-phenylethylamino)propan-2-ol;hydrochloride | MLS000516282 | SMR000372878 | cid_16196804
Type:
Small organic molecule
Emp. Form.:
C21H35NO2
Mol. Mass.:
333.5081
SMILES:
CC(C)C1CCC(C)CC1OCC(O)CNC(C)c1ccccc1
Structure:
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