Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM37642
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM37642
Synonyms:
6-[4-(4-phenylquinazolin-2-yl)piperazin-1-yl]carbonylcyclohex-3-ene-1-carboxylic acid | 6-[4-(4-phenylquinazolin-2-yl)piperazine-1-carbonyl]cyclohex-3-ene-1-carboxylic acid | 6-[oxo-[4-(4-phenyl-2-quinazolinyl)-1-piperazinyl]methyl]-1-cyclohex-3-enecarboxylic acid | MLS000078208 | SMR000041175 | cid_660299
Type:
Small organic molecule
Emp. Form.:
C26H26N4O3
Mol. Mass.:
442.5096
SMILES:
OC(=O)C1CC=CCC1C(=O)N1CCN(CC1)c1nc(-c2ccccc2)c2ccccc2n1 |c:5|
Structure:
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