Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM42357
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42357
Synonyms:
1-(4-chlorophenyl)-3-(3-imidazol-1-ylpropyl)urea | 1-(4-chlorophenyl)-3-[3-(1-imidazolyl)propyl]urea | MLS000087712 | N-(4-chlorophenyl)-N'-[3-(1H-imidazol-1-yl)propyl]urea | SMR000023933 | cid_2804810
Type:
Small organic molecule
Emp. Form.:
C13H15ClN4O
Mol. Mass.:
278.737
SMILES:
Clc1ccc(NC(=O)NCCCn2ccnc2)cc1
Structure:
Search PDB for entries with ligand similarity: