Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61833
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61833
Synonyms:
(E)-3-(1-phenyl-3-pyridin-3-yl-pyrazol-4-yl)-1-pyrrolidin-1-yl-prop-2-en-1-one | (E)-3-(1-phenyl-3-pyridin-3-ylpyrazol-4-yl)-1-pyrrolidin-1-ylprop-2-en-1-one | (E)-3-[1-phenyl-3-(3-pyridinyl)-4-pyrazolyl]-1-(1-pyrrolidinyl)-2-propen-1-one | (E)-3-[1-phenyl-3-(3-pyridyl)pyrazol-4-yl]-1-pyrrolidino-prop-2-en-1-one | MLS001003806 | SMR000347654 | cid_2381666
Type:
Small organic molecule
Emp. Form.:
C21H20N4O
Mol. Mass.:
344.4097
SMILES:
O=C(\C=C\c1cn(nc1-c1cccnc1)-c1ccccc1)N1CCCC1
Structure:
Search PDB for entries with ligand similarity: