Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM59994
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
IC50
>59642±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM59994
Synonyms:
6-[[4-(4-chloranylphenoxy)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid | 6-[[4-(4-chlorophenoxy)anilino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid | 6-[[4-(4-chlorophenoxy)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid | 6-{[4-(4-chlorophenoxy)anilino]carbonyl}-3-cyclohexene-1-carboxylic acid | MLS000704600 | SMR000231117 | cid_4990949
Type:
Small organic molecule
Emp. Form.:
C20H18ClNO4
Mol. Mass.:
371.814
SMILES:
OC(=O)C1CC=CCC1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 |c:5|
Structure:
Search PDB for entries with ligand similarity: