Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM61787
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61787
Synonyms:
1-(2-methylphenoxy)-3-[4-[3-(2-methylphenoxy)-2-oxidanyl-propyl]piperazin-1-yl]propan-2-ol | 1-[4-[2-hydroxy-3-(2-methylphenoxy)propyl]-1-piperazinyl]-3-(2-methylphenoxy)-2-propanol | 1-[4-[2-hydroxy-3-(2-methylphenoxy)propyl]piperazin-1-yl]-3-(2-methylphenoxy)propan-2-ol | 1-[4-[2-hydroxy-3-(2-methylphenoxy)propyl]piperazino]-3-(2-methylphenoxy)propan-2-ol | MLS000856374 | SMR000279319 | cid_2879592
Type:
Small organic molecule
Emp. Form.:
C24H34N2O4
Mol. Mass.:
414.5378
SMILES:
Cc1ccccc1OCC(O)CN1CCN(CC(O)COc2ccccc2C)CC1
Structure:
Search PDB for entries with ligand similarity: