Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM58193
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y2.
EC50
8693±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM58193
Synonyms:
1-(3,4-dichlorophenyl)-3-[2-[2,6-dinitro-4-(trifluoromethyl)anilino]ethyl]thiourea | 1-(3,4-dichlorophenyl)-3-[2-[[2,6-dinitro-4-(trifluoromethyl)phenyl]amino]ethyl]thiourea | MLS000833819 | N-(3,4-dichlorophenyl)-N'-{2-[2,6-dinitro-4-(trifluoromethyl)anilino]ethyl}thiourea | SMR000457540 | cid_2803877
Type:
Small organic molecule
Emp. Form.:
C16H12Cl2F3N5O4S
Mol. Mass.:
498.264
SMILES:
[O-][N+](=O)c1cc(cc(c1NCCNC(=S)Nc1ccc(Cl)c(Cl)c1)[N+]([O-])=O)C(F)(F)F
Structure:
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