Reaction Details Report a problem with these data
Target
Phosphotransferase
Ligand
BDBM62010
Substrate
n/a
Meas. Tech.
Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series
IC50
25000±n/a nM
Citation
 PubChem, PC Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphotransferase
Synonyms:
hexokinase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51160.00
Organism:
Trypanosoma brucei
Description:
gi_70832125
Residue:
471
Sequence:
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVATMISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPISMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKGGSGVGAALISAIVADGK
  
Inhibitor
Name:
BDBM62010
Synonyms:
2-(p-anisoylamino)-4-phenyl-benzoic acid | 2-[(4-methoxybenzoyl)amino]-4-phenylbenzoic acid | 2-[(4-methoxyphenyl)carbonylamino]-4-phenyl-benzoic acid | 2-[[(4-methoxyphenyl)-oxomethyl]amino]-4-phenylbenzoic acid | KSC-09-184 | KUC105923N | cid_46245545
Type:
Small organic molecule
Emp. Form.:
C21H17NO4
Mol. Mass.:
347.364
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(ccc1C(O)=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: