Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62074
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
7020±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62074
Synonyms:
1,1'-[(4,6-dimethoxy-1,3-phenylene)disulfonyl]dipiperidine | 1-(2,4-dimethoxy-5-piperidin-1-ylsulfonyl-phenyl)sulfonylpiperidine | 1-(2,4-dimethoxy-5-piperidin-1-ylsulfonylphenyl)sulfonylpiperidine | 1-(2,4-dimethoxy-5-piperidinosulfonyl-phenyl)sulfonylpiperidine | 1-[2,4-dimethoxy-5-(1-piperidinylsulfonyl)phenyl]sulfonylpiperidine | MLS000052046 | SMR000078608 | cid_1506525
Type:
Small organic molecule
Emp. Form.:
C18H28N2O6S2
Mol. Mass.:
432.555
SMILES:
COc1cc(OC)c(cc1S(=O)(=O)N1CCCCC1)S(=O)(=O)N1CCCCC1
Structure:
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