Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62076
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
23897±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62076
Synonyms:
2-[2-[1-hydroxybut-3-yn-2-yl-(phenylmethyl)amino]ethyl-(phenylmethyl)amino]-3-butyn-1-ol | 2-[2-[1-oxidanylbut-3-yn-2-yl-(phenylmethyl)amino]ethyl-(phenylmethyl)amino]but-3-yn-1-ol | 2-[benzyl-[2-[benzyl(1-hydroxybut-3-yn-2-yl)amino]ethyl]amino]but-3-yn-1-ol | 2-[benzyl-[2-[benzyl(1-methylolprop-2-ynyl)amino]ethyl]amino]but-3-yn-1-ol | MLS000104469 | SMR000054404 | cid_2827417
Type:
Small organic molecule
Emp. Form.:
C24H28N2O2
Mol. Mass.:
376.4913
SMILES:
OCC(C#C)N(CCN(Cc1ccccc1)C(CO)C#C)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: