Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62167
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
10381±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62167
Synonyms:
(5S)-1-(3-methylpentyl)-N-phenyl-5-(phenylmethyl)-4,5-dihydroimidazol-2-amine | (5S)-5-benzyl-1-(3-methylpentyl)-N-phenyl-4,5-dihydroimidazol-2-amine | MLS001368626 | SMR000752731 | [(5S)-5-benzyl-1-(3-methylpentyl)-2-imidazolin-2-yl]-phenyl-amine | cid_24856245
Type:
Small organic molecule
Emp. Form.:
C22H29N3
Mol. Mass.:
335.4858
SMILES:
CCC(C)CCN1[C@@H](Cc2ccccc2)CN=C1Nc1ccccc1 |c:17|
Structure:
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