Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM46667
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds
Ki
110±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay (2010)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM46667
Synonyms:
2-phenyl-1,2-benzothiazol-3-one | 2-phenyl-1,2-benzothiazol-3-one (1) | MLS-0107957.0001 | acs.jmedchem.1c00409_ST.178 | cid_164981
Type:
Small organic molecule
Emp. Form.:
C13H9NOS
Mol. Mass.:
227.282
SMILES:
O=c1n(sc2ccccc12)-c1ccccc1
Structure:
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