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Target
Delta-type opioid receptor
Ligand
BDBM54836
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay
IC50
32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM54836
Synonyms:
4-[1-[(7-chloro-4-quinolinyl)hydrazo]propylidene]-1-cyclohexa-2,5-dienone | 4-[1-[2-(7-chloranylquinolin-4-yl)hydrazinyl]propylidene]cyclohexa-2,5-dien-1-one | 4-[1-[2-(7-chloroquinolin-4-yl)hydrazinyl]propylidene]cyclohexa-2,5-dien-1-one | 4-[1-[N'-(7-chloro-4-quinolyl)hydrazino]propylidene]cyclohexa-2,5-dien-1-one | MLS001173902 | SMR000590556 | cid_6036600
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O
Mol. Mass.:
325.792
SMILES:
CCC(N=Nc1ccnc2cc(Cl)ccc12)c1ccc(O)cc1 |w:3.2|
Structure:
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