Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM62189
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay
EC50
1600±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM62189
Synonyms:
4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(dimethylamino)-2-phenyl-ethyl]benzamide | 4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(dimethylamino)-2-phenylethyl]benzamide | MLS-0355913.0001 | N-[2-(dimethylamino)-2-phenyl-ethyl]-4-[[(4-ethanoylphenyl)sulfonylamino]methyl]benzamide | cid_16294686
Type:
Small organic molecule
Emp. Form.:
C26H29N3O4S
Mol. Mass.:
479.591
SMILES:
CN(C)C(CNC(=O)c1ccc(CNS(=O)(=O)c2ccc(cc2)C(C)=O)cc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: