Reaction Details Report a problem with these data
Target
Trans-activator protein BZLF1
Ligand
BDBM62425
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA
IC50
111248±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA PubChem Bioassay (2010)[AID] 
Target
Name:
Trans-activator protein BZLF1
Synonyms:
BZLF1 | BZLF1_EBVB9 | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
26856.37
Organism:
Human herpesvirus 4
Description:
gi_82503229
Residue:
245
Sequence:
MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF
  
Inhibitor
Name:
BDBM62425
Synonyms:
4-[[(4-chlorophenyl)sulfonylamino]methyl]-N-piperonyl-cyclohexanecarboxamide | MLS000522173 | N-(1,3-benzodioxol-5-ylmethyl)-4-[[(4-chlorophenyl)sulfonylamino]methyl]-1-cyclohexanecarboxamide | N-(1,3-benzodioxol-5-ylmethyl)-4-[[(4-chlorophenyl)sulfonylamino]methyl]cyclohexane-1-carboxamide | SMR000132581 | cid_4340364
Type:
Small organic molecule
Emp. Form.:
C22H25ClN2O5S
Mol. Mass.:
464.962
SMILES:
Clc1ccc(cc1)S(=O)(=O)NCC1CCC(CC1)C(=O)NCc1ccc2OCOc2c1 |(3.08,-3.85,;4.41,-3.08,;4.41,-1.54,;5.75,-.77,;7.08,-1.54,;7.08,-3.08,;5.75,-3.85,;8.41,-.77,;7.64,.56,;9.18,-2.1,;9.75,,;11.08,-.77,;12.42,,;12.42,1.54,;13.75,2.31,;15.08,1.54,;15.08,,;13.75,-.77,;16.42,2.31,;16.42,3.85,;17.75,1.54,;19.08,2.31,;20.42,1.54,;20.42,,;21.75,-.77,;23.09,,;24.54,-.47,;25.44,.77,;24.54,2.01,;23.09,1.54,;21.75,2.31,)|
Structure:
Search PDB for entries with ligand similarity: