Reaction Details Report a problem with these data
Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM62418
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
6542±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM62418
Synonyms:
MLS000051274 | N-[1,3-bis(oxidanylidene)-2-(oxolan-2-ylmethyl)isoindol-5-yl]-4-(propanoylamino)benzamide | N-[1,3-diketo-2-(tetrahydrofurfuryl)isoindolin-5-yl]-4-propionamido-benzamide | N-[1,3-dioxo-2-(2-oxolanylmethyl)-5-isoindolyl]-4-(1-oxopropylamino)benzamide | N-[1,3-dioxo-2-(oxolan-2-ylmethyl)isoindol-5-yl]-4-(propanoylamino)benzamide | N-[1,3-dioxo-2-(tetrahydro-2-furanylmethyl)-2,3-dihydro-1H-isoindol-5-yl]-4-(propionylamino)benzamide | SMR000079301 | cid_2966346
Type:
Small organic molecule
Emp. Form.:
C23H23N3O5
Mol. Mass.:
421.4458
SMILES:
CCC(=O)Nc1ccc(cc1)C(=O)Nc1ccc2C(=O)N(CC3CCCO3)C(=O)c2c1
Structure:
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