Reaction Details Report a problem with these data
Target
Heat shock factor protein 1
Ligand
BDBM63402
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50
>195000±0 nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM63402
Synonyms:
MLS000729334 | N-(1,3-benzodioxol-5-yl)-2-[1-(3-hydroxypropyl)tetrazol-5-yl]sulfanylacetamide | N-(1,3-benzodioxol-5-yl)-2-[[1-(3-hydroxypropyl)-5-tetrazolyl]thio]acetamide | N-(1,3-benzodioxol-5-yl)-2-[[1-(3-hydroxypropyl)tetrazol-5-yl]thio]acetamide | N-(1,3-benzodioxol-5-yl)-2-[[1-(3-oxidanylpropyl)-1,2,3,4-tetrazol-5-yl]sulfanyl]ethanamide | N-1,3-benzodioxol-5-yl-2-{[1-(3-hydroxypropyl)-1H-tetrazol-5-yl]thio}acetamide | SMR000307612 | cid_5295847
Type:
Small organic molecule
Emp. Form.:
C13H15N5O4S
Mol. Mass.:
337.354
SMILES:
OCCCn1nnnc1SCC(=O)Nc1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: