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Target
Serine/threonine-protein phosphatase
Ligand
BDBM64794
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
2483±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM64794
Synonyms:
4-O-[3-cyclopropyl-7-methyl-6,8-dioxo-2-(3-propan-2-yloxypropyl)isoquinolin-7-yl] 1-O-methyl butanedioate | CMLD004055 | MLS000438605 | O4-[3-cyclopropyl-7-methyl-6,8-bis(oxidanylidene)-2-(3-propan-2-yloxypropyl)isoquinolin-7-yl] O1-methyl butanedioate | SMR000452656 | butanedioic acid O4-[3-cyclopropyl-7-methyl-6,8-dioxo-2-(3-propan-2-yloxypropyl)-7-isoquinolinyl] ester O1-methyl ester | cid_16745656 | succinic acid O4-[3-cyclopropyl-2-(3-isopropoxypropyl)-6,8-diketo-7-methyl-7-isoquinolyl] ester O1-methyl ester
Type:
Small organic molecule
Emp. Form.:
C24H31NO7
Mol. Mass.:
445.5054
SMILES:
COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(CCCOC(C)C)C=C2C1=O |c:29,t:13,15|
Structure:
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