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Target
ATP-dependent molecular chaperone HSP82
Ligand
BDBM64541
Substrate
n/a
Meas. Tech.
Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
EC50
>150000±0 nM
Citation
 PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 PubChem Bioassay (2010)[AID] 
Target
Name:
ATP-dependent molecular chaperone HSP82
Synonyms:
heat shock protein 90
Type:
Enzyme Catalytic Domain
Mol. Mass.:
80784.12
Organism:
Candida albicans
Description:
gi_994798
Residue:
707
Sequence:
MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
  
Inhibitor
Name:
BDBM64541
Synonyms:
1-[2-(dimethylamino)ethylamino]-3-methyl-2-prop-2-enyl-4-pyrido[1,2-a]benzimidazolecarbonitrile | 1-[2-(dimethylamino)ethylamino]-3-methyl-2-prop-2-enyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | 1-[2-(dimethylamino)ethylamino]-3-methyl-2-prop-2-enylpyrido[1,2-a]benzimidazole-4-carbonitrile | 2-allyl-1-[2-(dimethylamino)ethylamino]-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | MLS000081312 | SMR000045230 | cid_664345
Type:
Small organic molecule
Emp. Form.:
C20H23N5
Mol. Mass.:
333.4301
SMILES:
CN(C)CCNc1c(CC=C)c(C)c(C#N)c2nc3ccccc3n12
Structure:
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