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Target
ATP-dependent molecular chaperone HSP82
Ligand
BDBM64543
Substrate
n/a
Meas. Tech.
Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
EC50
>160000±0 nM
Citation
 PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 PubChem Bioassay (2010)[AID] 
Target
Name:
ATP-dependent molecular chaperone HSP82
Synonyms:
heat shock protein 90
Type:
Enzyme Catalytic Domain
Mol. Mass.:
80784.12
Organism:
Candida albicans
Description:
gi_994798
Residue:
707
Sequence:
MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
  
Inhibitor
Name:
BDBM64543
Synonyms:
2-(1,3-benzothiazol-2-yl)-1-(2,4-dihydroxyphenyl)ethanone | 2-(1,3-benzothiazol-2-yl)-1-[2,4-bis(oxidanyl)phenyl]ethanone | MLS000048617 | SMR000060774 | cid_727520
Type:
Small organic molecule
Emp. Form.:
C15H11NO3S
Mol. Mass.:
285.318
SMILES:
Oc1ccc(C(=O)Cc2nc3ccccc3s2)c(O)c1
Structure:
Search PDB for entries with ligand similarity: