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Target
Streptokinase A
Ligand
BDBM65739
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression.
EC50
5439±1074 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression. PubChem Bioassay (2010)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM65739
Synonyms:
2-chloranyl-N-[3-cyano-4-(4-methoxyphenyl)sulfonyl-phenyl]benzamide | 2-chloro-N-[3-cyano-4-(4-methoxyphenyl)sulfonyl-phenyl]benzamide | 2-chloro-N-[3-cyano-4-(4-methoxyphenyl)sulfonylphenyl]benzamide | BRD-K68340261-001-01-6 | cid_1489476
Type:
Small organic molecule
Emp. Form.:
C21H15ClN2O4S
Mol. Mass.:
426.873
SMILES:
COc1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)c2ccccc2Cl)cc1C#N
Structure:
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