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Target
Delta-type opioid receptor
Ligand
BDBM65830
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay - Set 2
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM65830
Synonyms:
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[3-[(phenylmethyl)-propan-2-yl-amino]propyl]benzamide | 4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[3-[(phenylmethyl)-propan-2-ylamino]propyl]benzamide | KSC-5-249 | KUC103906N | N-[3-[benzyl(isopropyl)amino]propyl]-4-[(tosylamino)methyl]benzamide | N-[3-[benzyl(propan-2-yl)amino]propyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | cid_20968607
Type:
Small organic molecule
Emp. Form.:
C28H35N3O3S
Mol. Mass.:
493.661
SMILES:
CC(C)N(CCCNC(=O)c1ccc(CNS(=O)(=O)c2ccc(C)cc2)cc1)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: