Reaction Details Report a problem with these data
Target
Interleukin-8
Ligand
BDBM62332
Substrate
n/a
Meas. Tech.
SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2
IC50
8600±792 nM
Citation
 PubChem, PC SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Interleukin-8
Synonyms:
CXCL8 | IL8 | IL8_HUMAN | MDNCF-a | interleukin 8 precursor
Type:
PROTEIN
Mol. Mass.:
11104.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_577736
Residue:
99
Sequence:
MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
  
Inhibitor
Name:
BDBM62332
Synonyms:
1-[2-(4-chloranylphenoxy)ethyl]benzimidazol-2-amine | 1-[2-(4-chlorophenoxy)ethyl]-2-benzimidazolamine | 1-[2-(4-chlorophenoxy)ethyl]benzimidazol-2-amine | MLS-0350139.0001 | [1-[2-(4-chlorophenoxy)ethyl]benzimidazol-2-yl]amine | cid_761923
Type:
Small organic molecule
Emp. Form.:
C15H14ClN3O
Mol. Mass.:
287.744
SMILES:
Nc1nc2ccccc2n1CCOc1ccc(Cl)cc1
Structure:
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