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Target
Mucolipin-3
Ligand
BDBM46868
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify selective agonists of the Transient Receptor Potential Channels 3 (TRPML3)
EC50
4724±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify selective agonists of the Transient Receptor Potential Channels 3 (TRPML3): fluorescence-based cell-based dose response assay for TRPML3 agonists PubChem Bioassay (2010)[AID] 
Target
Name:
Mucolipin-3
Synonyms:
MCLN3_HUMAN | MCOLN3 | MCOLN3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64244.09
Organism:
Homo sapiens (Human)
Description:
Q8TDD5
Residue:
553
Sequence:
MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK
  
Inhibitor
Name:
BDBM46868
Synonyms:
5-chloranyl-N,N-diethyl-4-methyl-2-propoxy-benzenesulfonamide | 5-chloro-N,N-diethyl-4-methyl-2-propoxy-benzenesulfonamide | 5-chloro-N,N-diethyl-4-methyl-2-propoxybenzenesulfonamide | MLS000548862 | SMR000113714 | cid_1818631
Type:
Small organic molecule
Emp. Form.:
C14H22ClNO3S
Mol. Mass.:
319.847
SMILES:
CCCOc1cc(C)c(Cl)cc1S(=O)(=O)N(CC)CC
Structure:
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