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Target
Inward rectifier potassium channel 2
Ligand
BDBM43753
Substrate
n/a
Meas. Tech.
Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1
IC50
33369±35763 nM
Citation
 PubChem, PC Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 PubChem Bioassay (2010)[AID] 
Target
Name:
Inward rectifier potassium channel 2
Synonyms:
Irk1 | KCNJ2_MOUSE | Kcnj2 | inward rectifier potassium channel 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48383.35
Organism:
Mus musculus
Description:
gi_6680530
Residue:
428
Sequence:
MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPRPLRRESEI
  
Inhibitor
Name:
BDBM43753
Synonyms:
6-methyl-N-(phenylmethyl)-1H-benzimidazol-2-amine | MLS000081058 | N-benzyl-6-methyl-1H-benzimidazol-2-amine | SMR000047154 | benzyl-(6-methyl-1H-benzimidazol-2-yl)amine | cid_665867
Type:
Small organic molecule
Emp. Form.:
C15H15N3
Mol. Mass.:
237.2997
SMILES:
Cc1ccc2nc(NCc3ccccc3)[nH]c2c1
Structure:
Search PDB for entries with ligand similarity: