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Target
Inward rectifier potassium channel 2
Ligand
BDBM65871
Substrate
n/a
Meas. Tech.
Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1
IC50
19775±9192 nM
Citation
 PubChem, PC Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 PubChem Bioassay (2010)[AID] 
Target
Name:
Inward rectifier potassium channel 2
Synonyms:
Irk1 | KCNJ2_MOUSE | Kcnj2 | inward rectifier potassium channel 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48383.35
Organism:
Mus musculus
Description:
gi_6680530
Residue:
428
Sequence:
MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPRPLRRESEI
  
Inhibitor
Name:
BDBM65871
Synonyms:
5-bromanyl-N-(1-phenylethyl)thiophene-2-sulfonamide | 5-bromo-N-(1-phenylethyl)-2-thiophenesulfonamide | 5-bromo-N-(1-phenylethyl)thiophene-2-sulfonamide | MLS001197733 | SMR000559803 | cid_2942461
Type:
Small organic molecule
Emp. Form.:
C12H12BrNO2S2
Mol. Mass.:
346.263
SMILES:
CC(NS(=O)(=O)c1ccc(Br)s1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: