Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM60394
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
5501±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM60394
Synonyms:
2-[(1,1-diketo-1,2-benzothiazol-3-yl)thio]-N-phenyl-acetamide | 2-[(1,1-dioxo-1,2-benzothiazol-3-yl)sulfanyl]-N-phenylacetamide | 2-[(1,1-dioxo-1,2-benzothiazol-3-yl)thio]-N-phenylacetamide | 2-[[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]sulfanyl]-N-phenyl-ethanamide | MLS000118226 | SMR000095170 | cid_5307202
Type:
Small organic molecule
Emp. Form.:
C15H12N2O3S2
Mol. Mass.:
332.397
SMILES:
O=C(CSC1=NS(=O)(=O)c2ccccc12)Nc1ccccc1 |t:4|
Structure:
Search PDB for entries with ligand similarity: