Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65987
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
4555±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65987
Synonyms:
2-amino-N-(4-ethoxyanilino)-2-oxoethanimidoyl cyanide | 2-cyano-2-(p-phenetylhydrazono)acetamide | 2-cyano-2-[(4-ethoxyphenyl)hydrazinylidene]acetamide | 2-cyano-2-[(4-ethoxyphenyl)hydrazinylidene]ethanamide | 2-cyano-2-[(4-ethoxyphenyl)hydrazono]acetamide | MLS000538742 | SMR000160684 | cid_833671
Type:
Small organic molecule
Emp. Form.:
C11H12N4O2
Mol. Mass.:
232.2386
SMILES:
CCOc1ccc(NN=C(C#N)C(N)=O)cc1 |w:8.7|
Structure:
Search PDB for entries with ligand similarity: