Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65989
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
12940±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65989
Synonyms:
2-thiophenecarboxylic acid [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] ester | MLS000563358 | SMR000176881 | [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] thiophene-2-carboxylate | [(Z)-[1-azanyl-2-(2,4-dichlorophenyl)ethylidene]amino] thiophene-2-carboxylate | cid_9594345 | thiophene-2-carboxylic acid [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] ester
Type:
Small organic molecule
Emp. Form.:
C13H10Cl2N2O2S
Mol. Mass.:
329.202
SMILES:
Clc1ccc(CC(=N)NOC(=O)c2cccs2)c(Cl)c1
Structure:
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