Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66009
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
4837±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66009
Synonyms:
(E)-1-(5-Chloro-2-hydroxy-phenyl)-3-(5-chloro-1-methyl-1H-imidazol-2-yl)-propenone | (E)-1-(5-chloro-2-hydroxy-phenyl)-3-(5-chloro-1-methyl-imidazol-2-yl)prop-2-en-1-one | (E)-1-(5-chloro-2-hydroxyphenyl)-3-(5-chloro-1-methyl-2-imidazolyl)-2-propen-1-one | (E)-1-(5-chloro-2-hydroxyphenyl)-3-(5-chloro-1-methylimidazol-2-yl)prop-2-en-1-one | (E)-3-(5-chloranyl-1-methyl-imidazol-2-yl)-1-(5-chloranyl-2-oxidanyl-phenyl)prop-2-en-1-one | MLS000777855 | SMR000414240 | cid_5898134
Type:
Small organic molecule
Emp. Form.:
C13H10Cl2N2O2
Mol. Mass.:
297.137
SMILES:
Cn1c(Cl)cnc1\C=C\C(=O)c1cc(Cl)ccc1O
Structure:
Search PDB for entries with ligand similarity: