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Target
Vacuolar aminopeptidase 1
Ligand
BDBM37061
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
EC50
1363±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM37061
Synonyms:
(4-methoxy-1,3-benzothiazol-2-yl)-[4-(2-pyridyl)thiazol-2-yl]amine | 4-methoxy-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-1,3-benzothiazol-2-amine | 4-methoxy-N-[4-(2-pyridinyl)-2-thiazolyl]-1,3-benzothiazol-2-amine | MLS000045456 | SMR000027216 | cid_3240629
Type:
Small organic molecule
Emp. Form.:
C16H12N4OS2
Mol. Mass.:
340.423
SMILES:
COc1cccc2sc(Nc3nc(cs3)-c3ccccn3)nc12
Structure:
Search PDB for entries with ligand similarity: