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Target
Beta-lactamase
Ligand
BDBM66109
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase
IC50
>59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29494.42
Organism:
Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Description:
gi_60115532
Residue:
269
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGESGNYG
  
Inhibitor
Name:
BDBM66109
Synonyms:
2-(3-Furan-2-yl-4-methyl-pentyl)-isoindole-1,3-dione | 2-[3-(2-furanyl)-4-methylpentyl]isoindole-1,3-dione | 2-[3-(2-furyl)-4-methyl-pentyl]isoindoline-1,3-quinone | 2-[3-(furan-2-yl)-4-methyl-pentyl]isoindole-1,3-dione | 2-[3-(furan-2-yl)-4-methylpentyl]isoindole-1,3-dione | MLS000557321 | SMR000148238 | cid_4418419
Type:
Small organic molecule
Emp. Form.:
C18H19NO3
Mol. Mass.:
297.3484
SMILES:
CC(C)C(CCN1C(=O)c2ccccc2C1=O)c1ccco1
Structure:
Search PDB for entries with ligand similarity: