Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66281
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66281
Synonyms:
MLS000062685 | N-(4-morpholin-4-ylsulfonylphenyl)furan-2-carboxamide | N-(4-morpholinosulfonylphenyl)-2-furamide | N-[4-(4-morpholinylsulfonyl)phenyl]-2-furamide | N-[4-(4-morpholinylsulfonyl)phenyl]-2-furancarboxamide | SMR000071222 | cid_690606
Type:
Small organic molecule
Emp. Form.:
C15H16N2O5S
Mol. Mass.:
336.363
SMILES:
O=C(Nc1ccc(cc1)S(=O)(=O)N1CCOCC1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: