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Target
Bcl-2-like protein 11
Ligand
BDBM66329
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
7337±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66329
Synonyms:
2-[1-[(Z)-1-(2-chlorophenyl)-3-oxidanylidene-3-phenyl-prop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile | 2-[1-[(Z)-1-(2-chlorophenyl)-3-oxo-3-phenylprop-1-en-2-yl]-2-pyridinylidene]propanedinitrile | 2-[1-[(Z)-1-(2-chlorophenyl)-3-oxo-3-phenylprop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile | 2-[1-[(Z)-1-benzoyl-2-(2-chlorophenyl)vinyl]-2-pyridylidene]malononitrile | 2-{1-[(Z)-1-Benzoyl-2-(2-chloro-phenyl)-vinyl]-1H-pyridin-2-ylidene}-malononitrile | MLS000554390 | SMR000146707 | cid_5797751
Type:
Small organic molecule
Emp. Form.:
C23H14ClN3O
Mol. Mass.:
383.83
SMILES:
Clc1ccccc1\C=C(/N1C=CC=CC1=C(C#N)C#N)C(=O)c1ccccc1 |c:11,13|
Structure:
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