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Target
Bcl-2-like protein 11
Ligand
BDBM66362
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66362
Synonyms:
2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-6-oxidanylidene-piperidine-3-carboxylic acid | 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-6-oxo-3-piperidinecarboxylic acid | 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-6-oxopiperidine-3-carboxylic acid | 2-(3,4-dimethoxyphenyl)-6-keto-1-(4-methoxyphenyl)nipecotic acid | MLS000572098 | SMR000151106 | cid_4327966
Type:
Small organic molecule
Emp. Form.:
C21H23NO6
Mol. Mass.:
385.4104
SMILES:
COc1ccc(cc1)N1C(C(CCC1=O)C(O)=O)c1ccc(OC)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: