Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66366
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66366
Synonyms:
2-[(4-acetylanilino)-oxomethyl]-3-amino-4-(4-methoxyphenyl)-6-methyl-5-thieno[2,3-b]pyridinecarboxylic acid ethyl ester | 2-[(4-acetylphenyl)carbamoyl]-3-amino-4-(4-methoxyphenyl)-6-methyl-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester | MLS000538152 | SMR000161396 | cid_990684 | ethyl 2-[(4-acetylanilino)carbonyl]-3-amino-4-(4-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-5-carboxylate | ethyl 2-[(4-acetylphenyl)carbamoyl]-3-amino-4-(4-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-5-carboxylate | ethyl 3-azanyl-2-[(4-ethanoylphenyl)carbamoyl]-4-(4-methoxyphenyl)-6-methyl-thieno[2,3-b]pyridine-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C27H25N3O5S
Mol. Mass.:
503.57
SMILES:
CCOC(=O)c1c(C)nc2sc(C(=O)Nc3ccc(cc3)C(C)=O)c(N)c2c1-c1ccc(OC)cc1
Structure:
Search PDB for entries with ligand similarity: