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Target
Bcl-2-like protein 11
Ligand
BDBM63097
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM63097
Synonyms:
MLS000556132 | N-[2-(cyclopentylamino)-2-keto-1-(2-thienyl)ethyl]-N-(2,5-dimethoxyphenyl)propiolamide | N-[2-(cyclopentylamino)-2-oxidanylidene-1-thiophen-2-yl-ethyl]-N-(2,5-dimethoxyphenyl)prop-2-ynamide | N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2,5-dimethoxyphenyl)-2-propynamide | N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2,5-dimethoxyphenyl)prop-2-ynamide | Propynoic acid (cyclopentylcarbamoyl-thiophen-2-yl-methyl)-(2,5-dimethoxy-phenyl)-amide | SMR000173283 | cid_3216694
Type:
Small organic molecule
Emp. Form.:
C22H24N2O4S
Mol. Mass.:
412.502
SMILES:
COc1ccc(OC)c(c1)N(C(C(=O)NC1CCCC1)c1cccs1)C(=O)C#C
Structure:
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