Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM43075
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM43075
Synonyms:
4-[(2-Methoxy-4-thiocyanato-phenylamino)-methylene]-5-methyl-2-p-tolyl-2,4-dihydro-pyrazol-3-one | MLS000555034 | SMR000171658 | [3-methoxy-4-[[(Z)-[3-methyl-1-(4-methylphenyl)-5-oxidanylidene-pyrazol-4-ylidene]methyl]amino]phenyl] thiocyanate | [3-methoxy-4-[[(Z)-[3-methyl-1-(4-methylphenyl)-5-oxopyrazol-4-ylidene]methyl]amino]phenyl] thiocyanate | cid_5439913 | thiocyanic acid [3-methoxy-4-[[(Z)-[3-methyl-1-(4-methylphenyl)-5-oxo-4-pyrazolylidene]methyl]amino]phenyl] ester | thiocyanic acid [4-[[(Z)-[5-keto-3-methyl-1-(p-tolyl)-2-pyrazolin-4-ylidene]methyl]amino]-3-methoxy-phenyl] ester
Type:
Small organic molecule
Emp. Form.:
C20H18N4O2S
Mol. Mass.:
378.448
SMILES:
COc1cc(SC#N)ccc1N=Cc1c(C)[nH]n(-c2ccc(C)cc2)c1=O |w:11.11|
Structure:
Search PDB for entries with ligand similarity: