Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66716
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66716
Synonyms:
3-(4-Amino-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid ethyl ester | 3-(4-aminophenyl)-2-(1,3-dioxo-2-isoindolyl)propanoic acid ethyl ester;hydrochloride | 3-(4-aminophenyl)-2-phthalimido-propionic acid ethyl ester;hydrochloride | MLS001209785 | SMR000513785 | cid_2830981 | ethyl 3-(4-aminophenyl)-2-(1,3-dioxoisoindol-2-yl)propanoate;hydrochloride | ethyl 3-(4-aminophenyl)-2-[1,3-bis(oxidanylidene)isoindol-2-yl]propanoate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C19H18N2O4
Mol. Mass.:
338.3572
SMILES:
CCOC(=O)C(Cc1ccc(N)cc1)N1C(=O)c2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: