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Target
Bcl-2-like protein 11
Ligand
BDBM66869
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66869
Synonyms:
1-(4-Fluoro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid (2-hydroxy-benzylidene)-hydrazide | 1-(4-fluorophenyl)-5-keto-N'-[(E)-(6-ketocyclohexa-2,4-dien-1-ylidene)methyl]pyrrolidine-3-carbohydrazide | 1-(4-fluorophenyl)-5-oxidanylidene-N'-[(E)-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)methyl]pyrrolidine-3-carbohydrazide | 1-(4-fluorophenyl)-5-oxo-N'-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-3-pyrrolidinecarbohydrazide | 1-(4-fluorophenyl)-5-oxo-N'-[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]pyrrolidine-3-carbohydrazide | MLS001219189 | SMR000607668 | cid_5753762
Type:
Small organic molecule
Emp. Form.:
C18H16FN3O3
Mol. Mass.:
341.3363
SMILES:
Oc1ccccc1C=NNC(=O)C1CN(C(=O)C1)c1ccc(F)cc1 |w:8.9|
Structure:
Search PDB for entries with ligand similarity: