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Target
Bcl-2-like protein 11
Ligand
BDBM66871
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66871
Synonyms:
2-(3-Cyano-4-methoxymethyl-6-methyl-pyridin-2-ylsulfanyl)-N-(4-methyl-thiazol-2-yl)-acetamide | 2-[3-cyano-4-(methoxymethyl)-6-methyl-pyridin-2-yl]sulfanyl-N-(4-methyl-1,3-thiazol-2-yl)ethanamide | 2-[3-cyano-4-(methoxymethyl)-6-methylpyridin-2-yl]sulfanyl-N-(4-methyl-1,3-thiazol-2-yl)acetamide | 2-[[3-cyano-4-(methoxymethyl)-6-methyl-2-pyridinyl]thio]-N-(4-methyl-2-thiazolyl)acetamide | 2-[[3-cyano-4-(methoxymethyl)-6-methyl-2-pyridyl]thio]-N-(4-methylthiazol-2-yl)acetamide | MLS001223238 | SMR000613254 | cid_2993420
Type:
Small organic molecule
Emp. Form.:
C15H16N4O2S2
Mol. Mass.:
348.443
SMILES:
COCc1cc(C)nc(SCC(=O)Nc2nc(C)cs2)c1C#N
Structure:
Search PDB for entries with ligand similarity: