Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM67046
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM67046
Synonyms:
MLS002252862 | N-(2-chlorophenyl)-2-[[2-keto-2-(1-naphthylamino)ethyl]-methyl-amino]acetamide | N-(2-chlorophenyl)-2-[methyl-[2-(1-naphthalenylamino)-2-oxoethyl]amino]acetamide | N-(2-chlorophenyl)-2-[methyl-[2-(naphthalen-1-ylamino)-2-oxidanylidene-ethyl]amino]ethanamide | N-(2-chlorophenyl)-2-[methyl-[2-(naphthalen-1-ylamino)-2-oxoethyl]amino]acetamide | SMR001315197 | cid_4879323
Type:
Small organic molecule
Emp. Form.:
C21H20ClN3O2
Mol. Mass.:
381.855
SMILES:
CN(CC(=O)Nc1ccccc1Cl)CC(=O)Nc1cccc2ccccc12
Structure:
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