Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM67076
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM67076
Synonyms:
2-[2-[[[2-[(4-chlorophenyl)sulfamoyl]-4-nitro-phenyl]hydrazinylidene]methyl]phenoxy]ethanoic acid | 2-[2-[[[2-[(4-chlorophenyl)sulfamoyl]-4-nitro-phenyl]hydrazono]methyl]phenoxy]acetic acid | 2-[2-[[[2-[(4-chlorophenyl)sulfamoyl]-4-nitrophenyl]hydrazinylidene]methyl]phenoxy]acetic acid | MLS002251691 | SMR001314077 | cid_4990931
Type:
Small organic molecule
Emp. Form.:
C21H17ClN4O7S
Mol. Mass.:
504.9
SMILES:
OC(=O)COc1ccccc1CN=Nc1ccc(cc1S(=O)(=O)Nc1ccc(Cl)cc1)[N+]([O-])=O |w:13.14|
Structure:
Search PDB for entries with ligand similarity: