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Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM67421
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
3706±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM67421
Synonyms:
(3,4-Dimethoxy-benzylidene)-(2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine | 1-(3,4-dimethoxyphenyl)-N-[2-(2-furanyl)-3-imidazo[1,2-a]pyridinyl]methanimine | 1-(3,4-dimethoxyphenyl)-N-[2-(furan-2-yl)imidazo[1,2-a]pyridin-3-yl]methanimine | MLS000067559 | SMR000115905 | [2-(2-furyl)imidazo[1,2-a]pyridin-3-yl]-veratrylidene-amine | cid_707197
Type:
Small organic molecule
Emp. Form.:
C20H17N3O3
Mol. Mass.:
347.3673
SMILES:
COc1ccc(C=Nc2c(nc3ccccn23)-c2ccco2)cc1OC
Structure:
Search PDB for entries with ligand similarity: