Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM50919
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
5308±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM50919
Synonyms:
2-methoxyethyl 4-amino-3-(2-methoxyethyl)-2-sulfanylidene-1,3-thiazole-5-carboxylate | 2-methoxyethyl 4-azanyl-3-(2-methoxyethyl)-2-sulfanylidene-1,3-thiazole-5-carboxylate | 4-amino-3-(2-methoxyethyl)-2-sulfanylidene-5-thiazolecarboxylic acid 2-methoxyethyl ester | 4-amino-3-(2-methoxyethyl)-2-thioxo-4-thiazoline-5-carboxylic acid 2-methoxyethyl ester | MLS000565318 | SMR000152486 | cid_2402693
Type:
Small organic molecule
Emp. Form.:
C10H16N2O4S2
Mol. Mass.:
292.375
SMILES:
COCCOC(=O)c1sc(=S)n(CCOC)c1N
Structure:
Search PDB for entries with ligand similarity: