Reaction Details Report a problem with these data
Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM67443
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
6196±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM67443
Synonyms:
(6E)-6-[[(5-amino-1-tetrazolyl)amino]methylidene]-4-chloro-1-cyclohexa-2,4-dienone | (6E)-6-[[(5-aminotetrazol-1-yl)amino]methylene]-4-chloro-cyclohexa-2,4-dien-1-one | (6E)-6-[[(5-aminotetrazol-1-yl)amino]methylidene]-4-chlorocyclohexa-2,4-dien-1-one | (6E)-6-[[(5-azanyl-1,2,3,4-tetrazol-1-yl)amino]methylidene]-4-chloranyl-cyclohexa-2,4-dien-1-one | 2-[(5-Amino-tetrazol-1-ylimino)-methyl]-4-chloro-phenol | MLS001210703 | SMR000514438 | cid_5757447
Type:
Small organic molecule
Emp. Form.:
C8H7ClN6O
Mol. Mass.:
238.634
SMILES:
Nc1nnnn1N=Cc1cc(Cl)ccc1O |w:6.6|
Structure:
Search PDB for entries with ligand similarity: