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Target
Serine/threonine-protein kinase 33
Ligand
BDBM50132
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
25530±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM50132
Synonyms:
3-Amino-6-furan-2-yl-thieno[2,3-b]pyridine-2-carboxylic acid amide | 3-amino-6-(2-furanyl)-2-thieno[2,3-b]pyridinecarboxamide | 3-amino-6-(2-furyl)thieno[2,3-b]pyridine-2-carboxamide | 3-amino-6-(furan-2-yl)thieno[2,3-b]pyridine-2-carboxamide | 3-azanyl-6-(furan-2-yl)thieno[2,3-b]pyridine-2-carboxamide | MLS000552509 | SMR000146024 | cid_930395
Type:
Small organic molecule
Emp. Form.:
C12H9N3O2S
Mol. Mass.:
259.284
SMILES:
NC(=O)c1sc2nc(ccc2c1N)-c1ccco1
Structure:
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