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Target
Serine/threonine-protein kinase 33
Ligand
BDBM57351
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
>120000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM57351
Synonyms:
3-(2-furanylmethyl)-5,6-diphenyl-4-furo[2,3-d]pyrimidinimine | 3-(furan-2-ylmethyl)-5,6-diphenyl-furo[2,3-d]pyrimidin-4-imine | 3-(furan-2-ylmethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-imine | 3-Furan-2-ylmethyl-5,6-diphenyl-3H-furo[2,3-d]pyrimidin-4-ylideneamine | MLS000558643 | SMR000176070 | [3-(2-furfuryl)-5,6-diphenyl-furo[2,3-d]pyrimidin-4-ylidene]amine | cid_1106410
Type:
Small organic molecule
Emp. Form.:
C23H17N3O2
Mol. Mass.:
367.4
SMILES:
N=c1n(Cc2ccco2)cnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: